List of antagonists in The Simpsons

These are antagonists in The Simpsons, either being villains, or antagonists who are good guys, dependent on the situation.

Antagonists
Those who have had a significant role as an antagonist, are in bold.


 * Russ Cargill (voiced by Albert Brooks): Is the main antagonist of The Simpsons Movie.
 * Charles Montgomery Burns: Is the main antagonist of the series, though not appearing in every episode. His significant antagonistic roles include "Marge Gets a Job", "Lady Bouvier's Lover", and "Fraudcast News".
 * Sideshow Bob (voiced by Kelsey Grammer): Is the main antagonist of every episode about him.
 * Cecil Terwilliger: Secondary antagonist of "Brother from Another Series".
 * Francine Rhenquist: Antagonist of "Bye Bye Nerdie".
 * Krusty the Clown: Although not exactly a villain, Krusty has had an anti-heroic antagonist role in some episodes, name a few.
 * Snake Jailbird: Reccuring antagonist in the series.
 * Spud and Cooder: Main antagonists of "Bart Carny"
 * '''Francesca Terwilliger: Secondary antagonist of "The Italian Bob"
 * Gino Terwilliger: Tertiary antagonist of "The Italian Bob"
 * [[Gary Chalmers: Minor antagonist.
 * Artie Ziff (voiced by Jon Lovitz)
 * Cesar and Ugolin: In "The Crepes of Wrath"
 * Jebediah Springfield: In "Lisa the Iconoclast", he was a murderous pirate named Hans Sprungfeld.
 * Lyle Lanley: Main antagonist of "Marge vs. the Monorail".
 * Adil Hoxha: In "The Crepes of Wrath".
 * Larry Kidkill: In "Eight Misbehavin".
 * Moe Szyslak: Minority of being an antagonist.
 * Seymour​ Skinner: Sometimes an antagonist, trying to get Bart back into school.
 * Garth Motherloving: In "Sweets and Sour Marge".
 * Lionel Hutz: Main antagonist of his last appearance, "Realty Bites".
 * Troy McClure: Main antagonist of "A Fish Called Selma".
 * Aristotle Amadopolis: Rival of Charles Montgomery Burns, who is also an antagonist.
 * Fat Tony: Reccuring antagonist in the series, up until his death.
 * '''Fit Fat Tony: Replaced Fat Tony.
 * '''Herman Hermann: Reccuring antagonist.
 * '''Harper Jambowski: Main antagonist of "Friend with Benefit".
 * Simpson family: The protagonists of the series have had a few antagonistic roles.