1501 East Oak Street is a meth lab located on East Oak Street. Homer came here by accident after Marge gave him a misleading address. The owner is the Meth Guy. There is an open kitchen and druggies sitting on the couch doing drugs.
Homer is then caught in a gun fight and then a fire breaks out; Marge eventually saves Homer.
Homer seems completely clueless about the fact that 1501 East Oak is a meth lab.