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We're Getting Mutants in the MCU - The Loop
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Angelique Bouvier (nee Marceau) (1839-1935/1936) is Marge's great-great-grandmother. She had 9 children with Marcel Bouvier. She is also the great great great grandmother of Simpson Children.
Trivia
Her maiden name and her husband's first name (and his mime-like appearance) are based off the famous late French mime Marcel Marceau.
