David Bowie was an English musician.
Carol Berrera has a cat named 'Bowie'. This is because it has different-colored eyes, like David Bowie.
Principal Skinner mentioned Bowie in his fake retirement speech. 
- Episode – "She of Little Faith" (mentioned)
- Episode – "Teenage Mutant Milk-caused Hurdles" (mentioned)
- Episode – "Fears of a Clown" (mentioned)