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Dr. Simpson (her first name has never been revealed) is the chief of complicated surgeries at the invasive care clinic.


Homer is devastated when he can't find any successful Simpson men to prove to Lisa that there is no genetic condition causing intelligence deterioration. As a last-ditch effort, he grabs Dr. Simpson, who explains that the defective Simpson Gene is only on the Y (male) Chromosome. Dr. Simpson looks a lot like Lisa, but older, and her hair is more down than up. She is Homer's cousin.

Dr. Simpson later appears in "Catch 'Em if You Can" in a flashback of Uncle Tyrone's birthday last year. It is unknown if she attended his birthday this year. However, if she did, she most likely would have been killed in the tornado in Dayton at the hotel where he was staying.


Characters voiced by Tress MacNeille
Ms. Albright | Alice Glick | June Bellamy | Belle | Billy (actor) | Booberella | Colin | Cosine | Crazy Cat Lady | Michael D'Amico | David (Treehouse of Horror XVI) | Devan Woosterfield | Dia-Betty | Mia Farrow | Ginger Flanders | Mrs. Glick | Adil Hoxha | Bernice Hibbert | Cookie Kwan | Lester | Audrey McConnell | Medicine Woman | Mrs. Muntz | Lindsey Naegle | Manjula Nahasapeemapetilon | Opal | Poor Violet | Lois Pennycandy | Pepi | Phillips | Brunella Pommelhorst | Ronaldo (Blame It on Lisa) | Dr. Simpson | Agnes Skinner | Brandine Spuckler | Jitney Spuckler | Whitney Spuckler | Spud | Dolph Starbeam | Clara Stetson | Gino Terwilliger | Judith Terwilliger | Leslie Robin Swisher | Vicki Valentine | Plopper | Princess Diana