George Washington was the first President of the United States and the enemy of Hans Sprungfeld, a.k.a. Jebediah Springfield. They shared a brief, but intense fist fight where Jebediah almost killed him and ruined a part of a portrait being done of him. George Washington was forced to use fake teeth to pinch Jebediah but stopped fighting after intervention by his wife, who was making a U.S.A. flag.
Non-canonIn Treehouse of Horror III a zombified George Washington can be seen walking around Springfield Elementary School. Homer kills him again with his shotgun.
As George Washington is deceased most of his appearances are minor or in flashbacks or mentions during the series. George Washington appears in Treehouse of Horror episodes. such as in Treehouse of Horror III, He appears as a zombie walking around Springfield Elementary School. Where he is killed by Homer Simpson.
At the end of Frinkcoin, Mister Burns has a dream about dancing with him. George says Burns' looks familiar and asks if he fought alongside him in "the war". Burns affirms he was in the war (the American Revolution) but that they weren't on the same side.