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When Springfield was threatened to be destroyed by a bomb during the Trappuccino incident, the crater that would be formed was promoted as the "New Grand Canyon". During a commercial, a family appears on the Grand Canyon, saying it is a boring place.
It appears again on the episode "Fland Canyon", where the Simpsons and the Flanders are visiting the canyon. However, their tour guide fell off a cliff making both families stranded inside the canyon, so Homer and Ned decided to steal the supplies from a millionares camping site in order to survive.