Homer's car is green in this episode, rather than the usual pink.
There is a hedge around the Flanders' yard in this episode, instead of a fence.
The Simpsons' carpet is pink in this episode.
Marge's necklace is white when Homer throws their wedding photo in the trash and she enters the room, but turns back to its normal red color when she picks it up.
The person at the front of the ticket queue (presumably a scalper), bought 30,000 tickets but there would be a limit to how many tickets one person could purchase.
Maude says that Rod and Todd aren't allowed sugar however if you don't eat enough sugar you will get Hypoglycaemia, which can cause death.
When Homer imagines getting himself a wig modeled after Marge's trademark hairstyle after Bart pranked him, Homer in his imagination chuckles and says he doesn't need Marge anymore now that he can mimic her perfectly. In Secrets of a Successful Marriage, however, it's revealed that Homer literally depends on Marge to survive and is incapable of taking care of himself.
Ned gets disturbed by Homer breathing through his nose during prayer and Ned shouts "BREATHE THROUGH YOUR DAMN MOUTH!!!" at him, but in the Season 8 episode "Hurricane Neddy", Ned mentions to the Lord that he doesn't swear.
Terminator 2: Judgment Day: When Homer chases the Flanders as they try to escape in their car, he holds the golf clubs the same way as the T-1000 had shaped its arms. This then leads to Homer using the clubs to grab a hold of the car in the same manner as the T-1000. The scene where Homer walks through the hedges is also similar to the scene where the T-1000 walks through a barred door.
Vertigo: The scene where Flanders is walking up the square staircase is a reference to the bell tower from the Hitchcock film Vertigo.
When Homer changes the radio station, "I've Got Two Tickets to Paradise" by Eddie Money plays, so naturally, Homer sings along and copies the guitar riff.
While driving in his car, Homer is listening to Bobby McFerrin latest song entitled "I'm Worried (Need Money)" a spoof of McFerrin's late 1980s one-hit wonder, "Don't Worry (Be Happy)."
The scene were Homer enters the bush to leave Ned's garage became a popular internet meme, often retouched to show Homer wearing the colors of one team, then reemerging wearing the colors of another.
This is one of the few times where Ned expresses anger with Homer.
This was the first episode to deal with the "reset button" theory.
During the scene in which Homer scorns Flanders as usual, there's a caption at the bottom saying "Thursday 8:00 PM", it references the original start time and date for Simpsons episodes before FOX moved it to Sundays.
The soup kitchen that Flanders takes Homer to is called Helter Shelter. The name is a refferece to the non-fiction book Helter Skelter that documented the Manson Family murders of the '70s. The same name is also used as a title to an episode in the 14th season.