- “You know, if you were only old enough to grow a bad teenaged moustache, I'd go out with you in a second.”
- ―Laura Powers[src]
Laura and Ruth Powers (Laura's mother) moved into the house next door when the Winfields moved out. Marge Simpson and Ruth became fast friends; so did Laura and Bart Simpson. After Laura made Bart faint, Bart developed a crush on her, but he later had his heart broken when he found out that she and Jimbo Jones were in a relationship. After Bart prank called Moe's Tavern, Laura chose that Jimbo was no good for her and said that she would date Bart if he were a little older: "If you had a bad teenage mustache, I'd go out with you in a second." She then kissed Bart. Since "New Kid on the Block", what becomes of their relationship is unknown.
Laura appears to be no longer living with her mother, but she is still in Springfield. According to "The Strong Arms of the Ma", Marge exclaims her surprise when she sees Ruth again at Springfield's muscle beach, calling Ruth an old neighbor, which implies they had moved out sometime after "New Kid on the Block". Near the end of the Trappuccino incident, she throws rocks at Homer Simpson when he returns to Springfield and raggedly appears in the crowd alongside her mother upon the climax of the dome's destruction.
Laura has a tomboyish, laid-back and quick witted charming personality. While outgoing and upbeat, she also displays a great deal of etiquette and manners, from which she owes to a strict and rigorous childhood. Because of her life of sojourning and traveling throughout the world, Laura grew to develop the ability to quickly learn and adapt to her surroundings, and make friends easily through her sociable and easy going nature. Laura also grew to be a prankster and a mild troublemaker akin to Bart, with knowledge how to turn adults away with a polished, polite, and well mannered face, and the simple wisdom that "the universal language of the wedgie is the quickest way to make friends." Despite this, it is believed she suffers from family issues due to her parent's divorce, and though she is affable and kind, is somewhat naive of less than wholesome peers seeking to take advantage of her friendship, including how appearances are not all that they seem to be, even if they seem to mesh well with one's preferences.
Her interests include rebellious quasi-thugs, poking dead bodies with a stick, and messing with people's minds. Her favorite restaurant is "Two Guys from Kabul." However, she dislikes authority and disco. Some of her extracurricular activities include babysitting, telling fortunes and dance instructing, being talented enough to teach even infants and cats. Due to being a military brat, she knows over eight languages, including Egyptian, Dutch, Afghani, and Japanese, and to English, even being able to distinguish regional dialects, like Deep South American to British. Her special skill is being able to proudly spitshoot farther than any boy, while her secret shame is enjoying trying on and wearing dresses in light of her tomboy self. 
Laura Powers has long brown hair and normally wears a white top, black pants, cream colored sneakers and a green jacket.
- On June 17, 2015, as part of the level 54 update, Laura was added to The Simpsons: Tapped Out as a premium character. You first need to build the Powers house to unlock her. In the associated questline, she is openly hostile towards Bart and attempts to avoid him while she is overly attached to Lisa.
- Laura's signature quote as found on Skybox trading cards is actually inaccurate; it was Bart who asked the question "J'ever have a Hertz Donut?" Laura only responded to counter in playful kind to the prank, saying "Hurts, don't it?"
- Laura's jacket has a corporal insignia on it.
- Laura is probably around 18 years old as she no longer lives with Ruth Powers (Laura's mother).
- Episode – "New Kid on the Block" (debut and only speaking appearance)
- Episode – "Marge on the Lam" (mentioned)
- Episode – "Another Simpsons Clip Show" (flashbacks)
- Episode – "Poppa's Got a Brand New Badge" (cameo)
- THOH – "Treehouse of Horror XII"
- – The Simpsons Movie (cameo)
- THOH – "Treehouse of Horror XXVII" (Dry Hard)
- Episode – "Marge the Lumberjill"
- Video game – The Simpsons: Tapped Out
- Comic story – Siege on Evergreen Terrace (cameo)
- Book – The Simpsons: A Complete Guide to Our Favorite Family
- Book – The Bart Book
- Book – Simpsons World: The Ultimate Episode Guide, Seasons 1-20