The Virtual Doctor website says that it's from the creators of Dragon Quest and SimSandwich. Dragon Quest is a series of RPGs released by Square Enix (originally released as Dragon Warrior in the US). SimSandwich is a reference to the Sim series of games, the most famous of which is The Sims. The Dragon Quest name is most likely coincidental and NOT meant as a reference to the real life game series of the same name.
The "You Got Leprosy" line said by the Virtual Doctor is modeled after AOL's "You Got Mail" greeting. Elwood Edwards recorded numerous greetings himself in 1989, including "You Got Mail," which were then incorporated into AOL in October 1989.