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Trivia
- Nelson and Lisa hold hands, referring to the episode where Lisa dates Nelson. They also discuss the time they were dating.
- Lisa and Nelson talk about the time they used to date. ("Lisa's Date With Density")
- Facebook is shown for the first time, although it was previously mentioned in "Waverly Hills 9-0-2-1-D'oh" and "Bart Gets a "Z"", and "Coming to Homerica" in the Chalkboard Gag.
- WALL-E's third appearance, the latest was Stealing First Base (during Itchy & Scratchy P.U.)
Goofs
Grampa already gave his inheritance to the Simpsons in Lisa vs. Malibu Stacy.
Cultural references
- The episode title is a pun on the "Mona Lisa" painting, which was previously punned in the episodes "Moaning Lisa," "Moe'N'a Lisa" and "Mona Leaves-a." And third to have Lisa's name in the title.
- Nelson's company Snot Wheels is a parody of the toy car company, Hot Wheels.
- Up: The 2009 Disney/Pixar movie is punned in P.U., the title of the Itchy & Scratchy cartoon Lisa and Bart watch in the car.
International premieres
- "Loan-a-Lisa" premiered on 14 October 2010 in the UK.
- The episode was broadcast two days after the theatrical release of The Social Network, a film on Mark Zuckerberg's founding of Facebook.
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