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Louis "Lou" Simpson was the son of Abraham Simpson I and Gabby Crouse. He married Zorina Ovadia and the couple had three children named Echardt Simpson, Bob Simpson and Twyla Simpson. He is also the maternal grandfather of Fernice Schedeen and Ingrid Schedeen. He is Orville's uncle, Abraham's great-uncle, Homer's great-granduncle, and Bart, Lisa, and Maggie's great-great-granduncle.

Appearances

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