- In keeping with the mystery of which state Springfield is in, this episode gives misleading clues. The map shown during the essay reading montage shows Springfield's state as being NT. The junk mail Homer receives shows the state as TA, and an enigmatic 6-digit zip code of 192005.
- In the office of the congressman from Springfield's state, there is a State Seal. It depicts an ear of corn, a star, a beaver and a nuclear power symbol.
- Barbara Bush wears a pearl necklace in the bathtub.
- In Dulles Airport, there is a sign reading "Bus Info" and then a phone number. This was the real phone number of the Simpsons' Art Director, and was drawn there without his knowledge.
- The plot (and title) of this episode is a play on Frank Capra's Mr. Smith Goes to Washington.
- Among the Washington DC landmarks visited are Dulles Airport (which is actually located in Chantilly, Virginia), the Watergate Hotel (where the family stays), the Kennedy Center for the Performing Arts, the IRS Building, the National Air and Space Museum, the Washington Monument, the Lincoln Memorial and the Jefferson Memorial.
- Truong Van Dinh had already won both the Westinghouse Talent Search and the NFL Punt, Pass, and Kick competition.
- The piano-playing satirist at the end of the episode is a reference to Mark Russell and Tom Lehrer. The song "The Deficit Rag" is very similar to Lehrer's "The Vatican Rag".
- The woman's suffrage display Lisa visits is likely a parody of Susan B. Anthony. When Lisa mentions "she later appeared on the highly unpopular 75¢ piece" this is a reference to the Susan Anthony dollar coins, which were often mistaken for quarters by vending machines and cashiers.
- The banner that reads "Brevity is... wit" is a reference to a line in Hamlet where Polonius says: "brevity is the soul of wit". The joke is that the banner is applying greater wit by increasing the brevity of the original Shakespeare line.
- Bob Arnold tells Lisa that there are quite a few women senators, but Lisa asserts that there are only two. At the time of airing there were indeed only two female senators: Nancy Kassebaum of Kansas and Barbara Mikulski of Maryland.
- During the White House tour, the Simpsons see a sign reading "On this spot, Richard Nixon bowled back-to-back 300 games," which Homer scoffs at. In real life, Nixon was an avid bowler; he even frequently bowled while he was President, finding that bowling fit well into his work schedule. However, it's unlikely that he ever bowled back-to-back 300 games.
- Then-President George H.W. Bush is featured briefly in this episode, and is portrayed in a positive, albeit hokey, light. Shortly after this episode aired, Bush disparaged The Simpsons in a speech. Thus, Bush appears in four later episodes (one of which is the season seven episode "Two Bad Neighbors") in a much more negative light.