watch 01:24 The Loop (TV) Do you like this video? Mrs. Grimes is the mother of Frank Grimes, Jr.. Not much is known to this character since she was only mentioned by Frank Grimes Jr. when he explained quickly to Homer about his appearance. Quotes - He used to like to hang out with hookers! - Frank Grimes Jr. Appearances Episode – "The Great Louse Detective" (mentioned) The Lockhart's Simpsons Crossover Retrieved from "https://simpsons.fandom.com/wiki/Mrs._Grimes?oldid=884146" Categories: Female characters Alive characters Characters Mothers Nameless characters One-Time Characters Mentioned characters Adults Non-speaking characters Singles Unseen characters Grimes family Community content is available under CC-BY-SA unless otherwise noted.