Due to the fact that a new trailer for The Simpsons Movie aired during the original American broadcast, several scenes were cut from the episode that aired on FOX:
The opening credits and couch gag were cut. The American version started with Declan Desmond's introduction, and the usual "created by Matt Groening" credits were shown over a shot of a playground.
In the first airing, the final minute of the episode was cut, ending after Marge and Homer hugged. The extended ending featured Homer and Desmond singing a duet.
The version that aired in Canada on local the same night did not feature the Movie trailer and as a result, the full version of the episode was aired. When the episode reaired on April 15, 2007, the cut material was restored, along with the original opening sequence.
Declan Desmond's documentary project parallels Michael Apted's Up series.
A parody of artist Andrew Wyeth's painting Christina's World, with Burns in the place of Christina, is visible after Burns pulls down Simpsons painting.
Frink's time machine is nearly identical to the time machine in the 1960 film The Time Machine.
Homer seems confused by the concept of Declan's documentaries and mocks his English accent, eventually concluding that the disparate filmings are unified by time travel, and that Declan is actually the Doctor from Doctor Who. Eric Idle was among a number of actors considered for the role of the Eighth Doctor in the 1996 Doctor Who TV Movie, though that role ultimately went to Paul McGann.
The movie "A Blind Man Climbs Mount Everest" is a reference to a real blind person who climbed up to Mount Everest.
The slideshow of pictures showing Moe growing up is a parody of Michael Jackson's looks throughout the years.
In one of the scenes from Homer's past, Homer creates a clay version of the play Equus.
The scene where Homer is apologizing to Declan Desmond in his editing room is parody to the Christmas Story "A Christmas Carol".
In the scene where Homer demonstrates the condiment pen, the condiments he dispenses form the numbers 0, 8, 1, and 2; each of the digits from the Van Halen album OU812.
This is the shortest Simpson episode (not including the Tracy Ullman shorts or Halloween segments) at 19 minutes and 49 seconds.
In the end, Homer and Declan sing the song Homer and the campers made up in How I Spent My Strummer Vacation.
The intervals take place in 1975, 1983, 1991, 1999, and 2007.
In a scene where Marge and Homer are interviewed the first time with children, a photo showing Lisa and Maggie is visible in the background, though Lisa is still a baby and Maggie is still unborn.
In the scene where Homer shows Marge his tattoo in the first part of the scene there is a wall behind the couch then when it zooms out for the second time there is a kitchen behind the couch.
Homer and Marge are in the same playground at eight but met in high school at seventeen.
Smithers is shown in the kindergarten at the same time as Homer and his friends. However, in "The Blunder Years" it is shown that he was a baby when Homer was 12 years old.
Professor Frink claims to never even have talked to a girl. Yet, we have met his son, in two previous episodes. In the boy's first appearance, Frink says his wife is going to kill him, for endangering their child (so, clearly he has been with a woman and has at least been married once). His wife may have separated from her loved one and/or divorced him as well.
In the scene where Homer is showing Declan the condiment pen and he asks whether he can use it on fish and chips, Homer says "I don't know, you can put horseradish on your dead mother for all I care." However, the condiment pen only dispenses ketchup, mayonnaise, mustard and relish.