This episode contradicts "Secrets of a Successful Marriage", where Homer revealed to the class Marge has had gray hair since she was a teenager and regularly dyed it. In this episode it appears this was the first time she understood of it. (But maybe Marge didn't understand she was gray underneath the dye).
Jessica Simpson could not be a relative to The Simpson Family, because she is a real life celebrity and her surname matching with the Simpsons could have been random similarity.
There are two Disco Stus during the opening of the seminar.
Homer explaining he will try to eat his leg to get freed, before Marge unties him, says it will take him 127 Hours.
The barbershop's name "Hairy Shearers" is a pun of Harry Shearer.
The instrumental tune from the ending is Love is Blue, by Paul Mauriat, which became the only number-one hit by a French artist to top the Billboard Hot 100 in America in 1968.
American Dad has a similar episode "Shallow Vows", as both episodes consists in that Marge and Francine chose stop to get a beauty treatment and this shows their true appearance (Marge's hair gray color / Francine's true grotesque appearance), this brings as result that their husbands finds Marge and Francine less attractives, and causes some problems in their relationship, especially when Marge and Francine finds the disgust of Homer and Stan about their new appearances.
When Marge assists Lisa in chasing down her macaroni Marconi, Milhouse wonders if Marge saw something scary, like the Count on Sesame Street.