
The Rosie O'Donnell Musical is a musical theater production involving the actress Rosie O'Donnell, and was implied to be struggling.
When Ned Flanders, after accidentally killing Hans Moleman due to shock from his vision of the latter's impending death by alligators in the sewer causing him to let go, is lamenting his cursed abilities to predict future people's deaths and begged God for relief, he then saw the musical theater holding the Rosie O'Donnell Musical right in front of him. As he touched the building beforehand, he then saw into the future and saw that it had closed within three days due to poor sales, although Ned dismissed the vision, citing that "he didn't need special powers to see that coming."