Catch-22 - Homer refers to the punctured keg of beer as being “so cold...so cold.” These are the words Snowden uses when hit and bleeding, in the novel Catch-22. Milhouse also says these words in the season seven episode "Home Sweet Homediddly-Dum-Doodily" after Bart complains that nothing happened to Milhouse after playing with the monkey in the Pier One wicker basket.
Annette tying the licorice into the message "Do Me" is based on the trick of tying a cherry stem into a knot with one's tongue.
The Octuplets' first words are "Mommy, will you let daddy come back" and "Cookie".
In Homer's dream about Apu's infidelity, Apu calls him a eunuch. When he wakes up and looks up "eunuch", Homer screams. A eunuch is a castrated male or a female who finds neither men or women sexually attractive (these days referred to as "asexual," though the term is also used to refer to someone who naturally feels no sexual attraction to either men or women without castration).
Homer also looks in the "U" section of the dictionary when searching for the word eunuch.
Even though the Squishees are replaced by Smooshies by the end of the episode, all future episodes featuring the Kwik-E-Mart still have Squishees. It's possible that Apu brought Squishees back after Smooshies were met with poor reception.
It is impossible to skate on grass.
When gets in bed after finding out Apu affair he is wearing his normal clothes, but he wakes after having a nightmare about Apu's affair is in his sleepwear.