As with any other Treehouse of Horror episode, this is one of several Simpsons episodes which are considered anthology episodes that feature mini-stories.
At the end of Attack of the 50-foot Eyesores, Kent Brockman warns people watching the news about the statues coming to life in their town, "Lock your doors, bar your windows, because the next advertisement you see could destroy your house and eat your family." In Lisa the Vegetarian, when Lisa remembers Kent eating meat during his news segment, he says the same sentence, though most of it is cut out.
When Lard Lad comes to life, he gives off a Godzilla roar.
The computer animated sequence was animated by Pacific Data Images, which would later be renamed PDI/DreamWorks (as a result of a merger), and be responsible for such hits as the How to Train Your Dragon,Shrek, Kung Fu Panda, and Madagascar movies.
When Homer is exploring the 3D world, he passes the library from the computer game "MYST", while being accompanied by music from the game.
In "Homer3" there are several background mathematics jokes, such as "P = NP" and "178212 + 184112 = 192212", which although false, appears true if evaluated to ten significant digits or less (such as on a typical pocket calculator); if true, it would disprove Fermat's last theorem, which had recently been proved. The writer for this segment, David S. Cohen, admitted that he put the formula in by writing a computer program to find the solution. For a fuller list and explanation, see the Wikipedia version of this page.
On the Gracie films logo, the jingle was played as a Myst/Philip Glass Homage as heard in Homer³. The scream usually heard from Treehouse of Horror IV and onwards is not heard.
The TV screen returns to its familiar color for the only time.
In "Homer3", there is a deleted scene of after Frink saying "The third dimension", he sees Lisa has turned out the lights and Frink draws on a blackboard, that scene is cut in some countries to save time, but it was left in US airings but it is cut in FXX reruns.
Another interesting thing to note is that this episode came out only a month before Pixar's Toy Story, which is considered the first entirely computer-animated film.
Krusty appears as the Headless Horseman, throws the head at the camera from The Legend of Sleepy Hollow.
In "Attack of the 50-Foot Eyesores", which is a parody of the film Attack of the 50 Foot Woman, there is a comical twist of the typical scenario of a tempter portrayed as a "devil on your shoulder": The devil statue destroys Springfield Elementary School, being tempted by Bart on its shoulder. It also references Pep Boys, with bobbleheads that have to be taken out of town in shopping carts due to their big heads.
In "Homer³", which is a parody of The Twilight Zone episode, Little Girl Lost and when he first sees the portal he says "It's like something from that Twilighty Show about that Zone. When Homer is trying to explain the 3D world he is stranded in, he says, "Uh... it's like... did anyone see the movie Tron?"
In "Nightmare on Evergreen Terrace," Groundskeeper Willie sinks into a sandbox, and as he does so, goes through numerous transformations as he sinks. This is a parody of the T-1000's death scene in Terminator 2: Judgment Day, in which the villain reverts to his previous transformations as he dies in a smelting pit.
When Kent Brockman gets grabbed by his giant monster self, it sounds like he is killed, however right at the end, he is seen alive and unharmed.
The impression given to the ground by a monster's foot is written normally. If the copyright information was carved into its foot in a legible way, it should create a backwards imprint.
When Bart decides he must engage in a showdown with Willie, a coffee mug randomly appears in the bottom left corner of the screen for a few frames.